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General Information
ZIRC
ZFIN ID: ZDB-GENE-001222-1
Gene Name: visual system homeobox 2
Gene Symbol: vsx2
Sequence Ontology ID : SO:0000704

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Previous Names: Vsx-2, alx (1), chx10 (1)

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and regulation of neural retina development. Predicted to localize to the  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
DISEASE ASSOCIATED WITH vsx2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
isolated microphthalmia 2 Microphthalmia, isolated 2 610093
Microphthalmia with coloboma 3 610092
DISEASE ASSOCIATED WITH vsx2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of transcription by RNA polymerase II (more)
Cellular Component nucleus (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 9)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA vsx2-201 (1) 1720
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDSNo data available
MARKER RELATIONSHIPS
vsx2Contained in: [BAC] DKEY-202B14 (1) (order this)
vsx2Encodes: [cDNA] MGC:66294 (1) (order this), MGC:85859 (1) (order this), MGC:191377 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131462 (1) 1712bp
Genomic GenBank:BX005320 (1) 142827bp
Select Tool
Polypeptide UniProtKB:O42477 (1) 393aa
Sequence Clusters UniGene:75766 (1)
Sequence Information (all 24)
ORTHOLOGY for vsx2 (Chr: 17)
CITATIONS (71)