ZFIN ID: ZDB-GENE-001222-1
Gene Name: visual system homeobox 2
Gene Symbol: vsx2
Sequence Ontology ID : SO:0000704

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Previous Names: Vsx-2, alx (1), chx10 (1)

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 54 figures from 26 publications
Directly Submitted Expression Data: 5 figures (9 images) from Thisse et al., 2004 [MGC:66294]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: 5 figures from 3 publications
Observed in:
DISEASE ASSOCIATED WITH vsx2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
isolated microphthalmia 2 Microphthalmia, isolated 2 610093
microphthalmia Microphthalmia, isolated 2 610093
Microphthalmia with coloboma 3 610092
DISEASE ASSOCIATED WITH vsx2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of transcription by RNA polymerase II (more)
Cellular Component nucleus (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR003654 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR023339 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • PROSITE:PS50803 (1)
  • PROSITE:PS51496 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF03826 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA vsx2-001 (1) 1720
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM vsx2
    MARKER RELATIONSHIPS
    vsx2Contained in: [BAC] DKEY-202B14 (1) (order this)
    vsx2Encodes: [cDNA] MGC:66294 (1) (order this), MGC:85859 (1) (order this), MGC:191377 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131462 (1) 1712bp
    Genomic GenBank:BX005320 (1) 142827bp
    Select Tool
    Polypeptide UniProtKB:O42477 (1) 393aa
    Sequence Clusters UniGene:75766 (1)
    Sequence Information (all 24)
    OTHER vsx2 GENE PAGES
  • Alliance (1)
  • Gene:796163 (1)
  • VEGA:OTTDARG00000024821 (1)
  • Ensembl(GRCz11):ENSDARG00000005574 (1)
  • ORTHOLOGY for vsx2 (Chr: 17)
    CITATIONS (66)