ZFIN ID: ZDB-GENE-001212-6
Gene Name: ATPase, Na+/K+ transporting, alpha 2a polypeptide
Gene Symbol: atp1a2a
Previous Names: atp[a]2 (1), cb702 (1), fa10d04, fa10d05, wu:fa10d05 (1)
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 5 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb702]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Adult (90d-730d, breeding adult)
  brain, heart, Kupffer's vesicle, myotome (all 16) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-atp1a2a (1), MO2-atp1a2a (1)

Allele Type Mutagen Suppliers
la023718Tg Transgenic Insertion DNA
sa11860 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: 8 figures from 2 publications
    Observed in: determination of heart left/right asymmetry, determination of left/right symmetry, digestive tract development, embryonic heart tube development (all 19) expand

    Phenotype of Human Orthologue OMIM Phenotype ID
    Alternating hemiplegia of childhood 104290
    Migraine, familial basilar 602481
    Migraine, familial hemiplegic, 2 602481
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of left/right symmetry (more)
    Cellular Component cytosol (more)
    Molecular Function ATP binding (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005775 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • InterPro:IPR030333 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • Pfam:PF00702 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp1a2a-001 (1) 3907
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp1a2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atp1a2a Contained in: [BAC] DKEYP-35B8 (1)
    atp1a2a Encodes: [EST] cb702 (2), fa10d04 (1), fa10d05 (1)
    [cDNA] MGC:194325 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131683 (1) 3889 bp
    Genomic GenBank:BX294126 (1) 179476 bp
    Select Tool
    Polypeptide UniProtKB:B0S5Q5 (1) 1017 aa
    Sequence Clusters UniGene:43391 (1)
    Sequence Information (all 21)
    OTHER atp1a2a GENE PAGES
  • Gene:64609 (1)
  • VEGA:OTTDARG00000020015 (1)
  • Ensembl(Zv9):ENSDARG00000010472 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atp1a2a 2  
    Human ATP1A2 1 (1q23.2)
  • OMIM:182340
  • Gene:477
  • Mouse Atp1a2 1 ( 79.60 cM)
  • MGI:88106
  • Gene:98660
  • Orthology Details
    CITATIONS (26)