ZFIN ID: ZDB-GENE-001212-6
Gene Name: ATPase, Na+/K+ transporting, alpha 2a polypeptide
Gene Symbol: atp1a2a
Previous Names: atp[a]2 (1), cb702 (1), fa10d04, fa10d05, wu:fa10d05 (1)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 5 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb702]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Adult (90d-730d, breeding adult)
  brain, heart, Kupffer's vesicle, myotome (all 16) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la023718Tg Transgenic Insertion DNA
sa11860 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-atp1a2a (1), MO2-atp1a2a (1)
    PHENOTYPE
    Data: 8 figures from 2 publications
    Observed in: determination of heart left/right asymmetry, determination of left/right symmetry, digestive tract development, embryonic heart tube development (all 19) expand
    DISEASE ASSOCIATED WITH atp1a2a HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    alternating hemiplegia of childhood Alternating hemiplegia of childhood 104290
    familial hemiplegic migraine Migraine, familial basilar 602481
    Migraine, familial hemiplegic, 2 602481
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process determination of left/right symmetry (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 29)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005775 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • EC:3.6.3.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp1a2a-001 (1) 3907
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp1a2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    atp1a2aContained in: [BAC] DKEYP-35B8 (1)
    atp1a2aEncodes: [EST] cb702 (2), fa10d04 (1), fa10d05 (1)
    [cDNA] MGC:194325 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131683 (1) 3889bp
    Genomic GenBank:BX294126 (1) 179476bp
    Select Tool
    Polypeptide UniProtKB:B0S5Q5 (1) 1017aa
    Sequence Clusters UniGene:43391 (1)
    Sequence Information (all 21)
    OTHER atp1a2a GENE PAGES 
  • Gene:64609 (1)
  • VEGA:OTTDARG00000020015 (1)
  • Ensembl(GRCz10):ENSDARG00000010472 (1)
  • ORTHOLOGY for atp1a2a (Chr: 2) 
    Species Symbol Chromosome Accession # Evidence
    Human ATP1A2 1
  • Gene:477
  • OMIM:182340
  • HGNC:800
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Atp1a2 1
  • MGI:88106
  • Gene:98660
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (28)