Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-001212-6
Gene Name: ATPase, Na+/K+ transporting, alpha 2a polypeptide
Gene Symbol: atp1a2a
Previous Names: atp[a]2 (1), cb702 (1), fa10d04, fa10d05, wu:fa10d05 (1)
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 5 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb702]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Adult (90d-730d, breeding adult)
  brain, heart, Kupffer's vesicle, myotome (all 16) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la023718Tg, sa11860
Knockdown reagents: MO1-atp1a2a (1), MO2-atp1a2a (1)
PHENOTYPE
Data: 8 figures from 2 publications
Observed in: determination of heart left/right asymmetry, determination of left/right symmetry, digestive tract development, embryonic heart tube development (all 19) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Alternating hemiplegia of childhood 104290
Migraine, familial basilar 602481
Migraine, familial hemiplegic, 2 602481
GENE ONTOLOGY
Ontology GO Term
Biological Process determination of left/right symmetry (more)
Cellular Component cytosol (more)
Molecular Function ATP binding (more)
GO Terms (all 21)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005775 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • Pfam:PF00702 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp1a2a-001 (1) 3907
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp1a2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atp1a2a Contained in: [BAC] DKEYP-35B8 (1)
    atp1a2a Encodes: [EST] cb702 (2), fa10d04 (1), fa10d05 (1)
    [cDNA] MGC:194325 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131683 (1) 3889 bp
    Genomic GenBank:BX294126 (1) 179476 bp
    Select Tool
    Polypeptide UniProtKB:B0S5Q5 (1) 1017 aa
    Sequence Clusters UniGene:43391 (1)
    Sequence Information (all 21)
    OTHER atp1a2a GENE PAGES
  • Gene:64609 (1)
  • VEGA:OTTDARG00000020015 (1)
  • Ensembl(Zv9):ENSDARG00000010472 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atp1a2a 2  
    Human ATP1A2 1 (1q23.2)
  • OMIM:182340
  • Gene:477
  • Mouse Atp1a2 1 ( 79.60 cM)
  • MGI:88106
  • Gene:98660
  • Orthology Details
    CITATIONS (26)