atp1b1b

ID

ZDB-GENE-001127-4

Name

ATPase Na+/K+ transporting subunit beta 1b

Symbol

atp1b1b Nomenclature History

Previous Names

cb710 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to act upstream of or within potassium ion transport and sodium ion transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Is expressed in ectoderm; epidermal cell; integument; ionocyte progenitor cell; and nervous system. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human ATP1B1 (ATPase Na+/K+ transporting subunit beta 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

26 figures from 10 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb710 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atp1b1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
essential hypertension	Alliance	[Blood pressure regulation QTL]	145500

Associated With atp1b1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR000402	Sodium/potassium-transporting ATPase subunit beta
Homologous_superfamily	IPR038702	Sodium/potassium-transporting ATPase subunit beta superfamily