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General Information
ZIRC
ZFIN ID: ZDB-GENE-001103-4
Gene Name: cytochrome P450, family 19, subfamily A, polypeptide 1b
Gene Symbol: cyp19a1b
Sequence Ontology ID : SO:0001217

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Attributions

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Previous Names: CYP19a2 (1), cyp19b (2), AroB (2), aromatase B (1), brain aromatase (1), P450aromB (1), zgc:92614

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have heme binding activity; iron ion binding activity; and oxidoreductase activity. Involved in several processes, including response to estradiol; response to estrogen; and response to  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24593 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37991 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37992 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • uc39 Small Deletion Unknown Frameshift, Premature Stop TALEN
    uc40 Small Deletion Unknown Frameshift, Premature Stop TALEN
    zf1032 Small Deletion Exon 4 Unknown TALEN
    Targeting reagents:
    DISEASE ASSOCIATED WITH cyp19a1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    aromatase excess syndrome Aromatase excess syndrome 139300
    Aromatase deficiency 613546
    DISEASE ASSOCIATED WITH cyp19a1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to estradiol (more)
    Cellular Component integral component of membrane (more)
    Molecular Function heme binding (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    pseudogenic transcript cyp19a1b-001 (1) 4167
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp19a1b
    MARKER RELATIONSHIPS
    cyp19a1b Contained in: [BAC] CH211-286K11 (1) (order this)
    cyp19a1b Encodes: [cDNA] MGC:92614 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131642 (1) 3809 bp
    Genomic GenBank:AL954697 (1) 134798 bp
    Select Tool
    Polypeptide UniProtKB:Q5U870 (1) 511 aa
    Sequence Clusters UniGene:10461 (1)
    Sequence Information (all 30)
    ORTHOLOGY for cyp19a1b ( Chr: 25 )
    CITATIONS (229)