Gene

sox9b

ID
ZDB-GENE-001103-2
Name
SRY-box transcription factor 9b
Symbol
sox9b Nomenclature History
Previous Names
  • fb18d01
  • wu:fb18d01 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; embryonic pectoral fin morphogenesis; and iridophore differentiation. Predicted to localize to nucleus. Is expressed in several structures, including digestive system; head; nervous system; neural crest; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in 46,XX sex reversal 2; 46,XY sex reversal 10; and campomelic dysplasia. Orthologous to human SOX9 (SRY-box transcription factor 9).
Genome Resources
Note
None
Expression
All Expression Data
105 figures from 79 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
20 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sox9b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
campomelic dysplasia Alliance Acampomelic campomelic dysplasia 114290
campomelic dysplasia Alliance Campomelic dysplasia 114290
campomelic dysplasia Alliance Campomelic dysplasia with autosomal sex reversal 114290
Associated With sox9b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Domain IPR022151 Sox developmental protein N-terminal
Family IPR029548 Transcription factor SOX-9
Homologous_superfamily IPR036910 High mobility group box domain superfamily
Domain Details Per Protein
Protein Length High mobility group box domain High mobility group box domain superfamily Sox developmental protein N-terminal Transcription factor SOX-9
UniProtKB:Q9DFH1 407
UniProtKB:X1WBU9 151
UniProtKB:Q6NXE1 398
UniProtKB:Q8UV13 129
UniProtKB:Q5DLW5 360
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-sox9b Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations