Gene
nkx2.4b
- ID
- ZDB-GENE-000830-1
- Name
- NK2 homeobox 4b
- Symbol
- nkx2.4b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Is predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cell differentiation and regulation of transcription by RNA polymerase II. Acts upstream of or within hypothalamus development and thyroid gland development. Is expressed in several structures, including endocrine system; forebrain; neural keel; neural plate; and swim bladder. Orthologous to human NKX2-4 (NK2 homeobox 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 77 figures from 49 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox, conserved site | Homeobox domain | Homeobox domain, metazoa | Homeobox-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A5WVY6
|
307 | ||||
|
UniProtKB:B3DG83
|
307 | ||||
|
UniProtKB:Q9I8L7
|
307 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
nkx2.4b-201
(1)
|
1151 nt |
Interactions and Pathways
No data available
Plasmids
No data available