ZFIN ID: ZDB-GENE-000509-1
Gene Name: aryl hydrocarbon receptor nuclear translocator-like 1a
Gene Symbol: arntl1a    Nomenclature History

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Previous Names: bmal1, bmal1a (1), hif1b (1), wu:fa04g03 (1), zfBMAL1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Exhibits transcription regulatory region sequence-specific DNA binding activity. Contributes to DNA binding activity. Involved in several processes, including circadian rhythm; photoperiodism; and regulation of transcription, DNA-templated. Localizes to transcription regulator complex. Orthologous to human ARNTL (aryl hydrocarbon receptor nuclear translocator like).
Genome Resources: Alliance (1),  Gene:58098 (1),  Ensembl(GRCz11):ENSDARG00000006791 (2)
GENE EXPRESSION
All Expression Data: 16 figures from 11 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55263]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct803 Small Deletion Unknown Unknown ZINC_FINGER_NUCLEASE
sa24645 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38044 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arntl1a N/A 2
    MO2-arntl1a N/A 1
    PHENOTYPE
    Data: 2 figures from Jensen et al., 2012
    Observed in:
    DISEASE ASSOCIATED WITH arntl1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arntl1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription, DNA-templated (more)
    Cellular Component protein-containing complex (more)
    Molecular Function CONTRIBUTES_TO   DNA binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arntl1a-201 (1)    Ensembl 2343
    arntl1a-202 (1)    Ensembl 2326
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-arntl1a polyclonal Rabbit 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arntl1a No data available
    MARKER RELATIONSHIPS
    arntl1a Contained in: [BAC] CH211-244M13 (1)
    arntl1a Encodes: [EST] fa04g03 (1)
    [cDNA] MGC:55263 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131577 (1) 2343 nt
    Genomic GenBank:CR759966 (1) 142946 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZU37 (1) 626 aa
    Sequence Information (all 17)
    ORTHOLOGY for arntl1a ( Chr: 25 )
    CITATIONS (78)