Gene

tbx20

ID
ZDB-GENE-000427-7
Name
T-box transcription factor 20
Symbol
tbx20 Nomenclature History
Previous Names
  • ZF-TBX20 (1)
  • cb826 (1)
  • hrt
  • hrT (1)
  • whz
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including circulatory system development; cloaca development; and regulation of cardiac muscle cell proliferation. Predicted to localize to nuclear chromatin. Is expressed in cardiovascular system; digestive system; mesoderm; nervous system; and trunk. Human ortholog(s) of this gene implicated in atrial heart septal defect 4. Orthologous to human TBX20 (T-box transcription factor 20).
Genome Resources
Note
None
Expression
All Expression Data
61 figures from 48 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
21 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tbx20 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
atrial heart septal defect 4 Alliance Atrial septal defect 4 611363
Associated With tbx20 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018186 Transcription factor, T-box, conserved site
Family IPR001699 Transcription factor, T-box
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding
Homologous_superfamily IPR036960 T-box superfamily
Domain Details Per Protein
Protein Length p53-like transcription factor, DNA-binding T-box superfamily Transcription factor, T-box Transcription factor, T-box, conserved site
UniProtKB:B3DJG4 446
UniProtKB:Q9I9K7 446
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-tbx20 polyclonal IgG Rabbit
  • WB
Abcam plc
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations