Gene

cat

ID
ZDB-GENE-000210-20
Name
catalase
Symbol
cat Nomenclature History
Previous Names
  • fb68a12
  • wu:fb68a12 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have catalase activity and heme binding activity. Involved in response to copper ion. Predicted to localize to mitochondrion and peroxisome. Human ortholog(s) of this gene implicated in several diseases, including acatalasia; eye disease (multiple); lung disease (multiple); osteonecrosis; and pseudoxanthoma elasticum. Is expressed in digestive system; gill; head; muscle; and nervous system. Orthologous to human CAT (catalase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
29 figures from 21 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Albadri et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cat Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
acatalasia Alliance Acatalasemia 614097
Associated With cat Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR024708 Catalase active site
Binding_site IPR002226 Catalase haem-binding site
Domain IPR010582 Catalase immune-responsive domain
Domain IPR011614 Catalase core domain
Family IPR018028 Catalase, mono-functional, haem-containing
Family IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3
Family IPR040333 Catalase, clade 3
Homologous_superfamily IPR020835 Catalase superfamily
Domain Details Per Protein
Protein Length Catalase active site Catalase, clade 3 Catalase core domain Catalase haem-binding site Catalase immune-responsive domain Catalase, mono-functional, haem-containing Catalase, mono-functional, haem-containing, clades 1 and 3 Catalase superfamily
UniProtKB:Q7ZTT1 526
UniProtKB:Q9PT92 526
UniProtKB:A0A0R4II89 526
UniProtKB:A0A0R4IGK9 504
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-cat polyclonal Rabbit
Sigma-Aldrich
3
Ab4-cat polyclonal IgG Rabbit
  • IHC
Athens Research and Technology
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations