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ZIRC
ZFIN ID: ZDB-GENE-000128-8
Gene Name: developing brain homeobox 1a
Gene Symbol: dbx1a    Nomenclature History

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Previous Names: hlx-1 (1), hlx1 (1), fc15c04, H2.0-like homeobox 1, wu:fc15c04 (1), zgc:109861

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Involved in cell differentiation in spinal cord. Predicted to localize to the nucleus. Is expressed in several structures, including axial hypoblast; brain; neural tube; posterior neural rod; and prechordal plate. Orthologous to human DBX1 (developing brain homeobox 1).
Genome Resources: Alliance (1),  Gene:30394 (1),  Ensembl(GRCz11):ENSDARG00000086393 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34025 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dbx1a N/A 1
    MO2-dbx1a N/A 1
    MO3-dbx1a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dbx1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dbx1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell differentiation in spinal cord (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dbx1a-201 (1)    Ensembl 1433
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dbx1a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-3.5dbx1a:EGFP) dbx1a EGFP Danio rerio 2 4
    Tg(-3.5dbx1a:GFP) dbx1a GFP Danio rerio 1 2
    Tg(-3.5dbx1a:mCherry) dbx1a mCherry Danio rerio 1 2
    TgBAC(dbx1a:GAL4-VP16,myl7:mCherry) dbx1amyl7 GAL4mCherryVP16 Danio rerio 1 1
    MARKER RELATIONSHIPS
    dbx1a Contained in: [BAC] CH73-206B14 (1) (order this)
    dbx1a Encodes: [EST] fc15c04 (1) (order this), hlx1_est, IMAGE:7143589 (1) (order this)
    [cDNA] MGC:109861 (1) (order this), MGC:191281 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131158 (1) 1453 bp
    Genomic GenBank:CU929054 (1) 84566 bp
    Select Tool
    Polypeptide UniProtKB:B2GNV2 (1) 314 aa
    Sequence Clusters UniGene:8070 (1)
    Sequence Information (all 22)
    ORTHOLOGY for dbx1a ( Chr: 7 )
    CITATIONS (89)