FIGURE

Fig. 2

ID

ZDB-FIG-240126-27

Publication

Takesono et al., 2023 - Zinc oxide nanoparticles disrupt development and function of the olfactory sensory system impairing olfaction-mediated behaviour in zebrafish

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Fig. 2

ZnONP exposure induces OS responses in olfactory sensory neurons. (A-D) Confocal images of key limpet haemocyanin (KLH) positive axonal projections of olfactory sensory neurons (OSNs) (green) and mCherry expressing OS responding cells (red) in the OE and OB. The nuclei staining (blue) and white dotted lines, represent the outline of the OE and OB (A-D); olfactory glomeruli, yellow dotted rectangles in A-D; mediodorsal glomeruli, mdGs (Ai-Di); dorsolateral glomerulous, dlG (Aii-Dii); the cell bodies of OS responding OSNs, white arrows (B-D). Scale bar, 25 μm. (E, F) Illustrations of changes in olfactory tissues with (F) or without (E) ZnONP or dissolved Zn exposure to EpRE:mCherry zebrafish embryo-larvae. Control OSNs (green); OS responding OSNs (red); olfactory epitheium, OE; olfactory bulb, OB; Telencephalon, Tel. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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