FIGURE

Figure 6

ID
ZDB-FIG-230515-46
Publication
Bulk et al., 2023 - Holoprosencephaly with a Special Form of Anophthalmia Result from Experimental Induction of bmp4, Oversaturating BMP Antagonists in Zebrafish
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Figure 6

Scheme, summary of major findings. (A): Experimental induction of bmp4 results in a suppression of rx3 and shha/b with a consecutive suppression of cxcr4a and zic2a. The ANP is not splitting in a proper manner, resulting in a crypt-oculoid. Six3b and emx3 are found condensed at the midline. (B): scheme showing the pathological development of the ANP resulting from bmp4 induction, including a defect in the hypothalamic subduction. (C): brief summary of findings.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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