FIGURE
Figure 3
- ID
- ZDB-FIG-230515-43
- Publication
- Bulk et al., 2023 - Holoprosencephaly with a Special Form of Anophthalmia Result from Experimental Induction of bmp4, Oversaturating BMP Antagonists in Zebrafish
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Figure 3
(A): summary of experimental procedure: embryos were injected at 1-cell-stage and analyzed at 24 hpf or 48 hpf. (B–E): Brightfield-images at 48 hpf. We observed anophthalmia in F0 rx3 Crispants. (F–I): ISH for rx2 at 24 hpf. The expression of rx2 is absent in F0 rx3 Crispants at 24 hpf, correlating with the severity of the phenotype. (B,C,F,G): wildtype. (D,E,H,I): rx3-crispant. (B,D,F,H) dorsal view. (C,E,G,I) lateral view. scalebars indicate 250 µm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ Int. J. Mol. Sci.