FIGURE

Figure 4

ID

ZDB-FIG-230228-309

Publication

Yan et al., 2023 - The isl2a transcription factor regulates pituitary development in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Figure 4

Growth retardation in isl2a knockout zebrafish. (A) The Kaplan-Meier survival curve of isl2a^+/+ (n = 159), isl2a^+/− (n = 173), and isl2a^−/− (n = 253) larvae shows differences. (B) Male/female ratios in isl2a^+/+ (male/female = 20/6), isl2a^+/− (male/female = 42/10), and isl2a^−/− (male/female = 18/3). (C) The isl2a variant caused significant growth defects in 41 dpf zebrafish adults. Scale bar = 1 mm. (D) Comparison of developmental indicators, including body length, heart rate, eye size, and ear size, among isl2a^-/-, isl2a^+/+ and isl2a^+/- siblings at 5 dpf. (E) Comparison of three diameter lines of skull among different groups at 5 dpf. (F) Dynamic tracking of the body length of isl2a^-/- individuals and their isl2a^+/+ and isl2a^+/- siblings at 14 dpf, 41 dpf, 77 dpf, and 7.5 mpf. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Endocrinol (Lausanne)