FIGURE

Figure 2

ID

ZDB-FIG-230228-168

Publication

Sato et al., 2023 - Transgenic Zebrafish Expressing Rat Cytochrome P450 2E1 (CYP2E1): Augmentation of Acetaminophen-Induced Toxicity in the Liver and Retina

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Figure 2

Effects of acetaminophen on melanin contents of rat CYP2E1-TG larvae. EGFP fluorescence-negative (EGFP [−]) and -positive (EGFP [+]) F2 CYP2E1-transgenic larvae were exposed to 2.5 mM acetaminophen (APAP) from 24 hpf to 54 hpf for determination of melanin contents. Control means no treatment since APAP was dissolved in ZR solution. Each tube contained 18–20 larvae, and the melanin contents of three tubes were determined for each treatment (n = 3). Bars with different letters (a, b) are significantly different (p < 0.05). Inset images in the right are also shown. Asterisk indicates mild pericardial edema in inset image.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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