Fig. 2
- ID
- ZDB-FIG-230223-56
- Publication
- Perdikaris et al., 2021 - Behavioral and neurochemical profile of MK-801 adult zebrafish model: Forebrain β2-adrenoceptors contribute to social withdrawal and anxiety-like behavior
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Fig. 2. MK-801-treated zebrafish deficits in social communication and altered glutamatergic neurotransmission. (A-G) Social and non-social parameters using SI test: (A) Representative swimming behavior tracking of control (left) and MK-801-treated (right) zebrafish, (B) SI index, (C) Time spent in social and non–social zone, (D) Number of zone entries, (E) Latency to enter in social zone, (F) Total distance travelled, (G) Average velocity. (H-K) Social parameters estimated by MIS test: (H) representative swimming behavior tracings of control (left) and MK–801-treated (right) zebrafish, (I) MIS index, (J) Number of zone entries, (K) Latency to enter in mirror zone. (L, M) Altered mGluR5 protein levels determined by western blotting in (L) telencephalon and (M) diencephalic/mesencephalic complex in MK-801-treated zebrafish. Data are expressed as mean ± SEM, n = 15 or n = 4 per group for behavioral tests or western blot, respectively. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, compared to control group. |