FIGURE

Fig. 1

ID

ZDB-FIG-221210-9

Publication

Xiong et al., 2021 - SLC1A1 mediated glutamine addiction and contributed to natural killer T-cell lymphoma progression with immunotherapeutic potential

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Fig. 1

Metabolomic assay indicated aberrant glutamine metabolism in patients with NKTCL.

(a) Distinguished serum metabolites of NKTCL (red dots), PTCL (dark blue dots), and DLBCL (light blue dots), comparing with healthy volunteer, were overlaid on human metabolic reference map (KEGG: hsa01100) using Interactive Pathways Explorer v3 (iPath 3). Pathways involving amino acid metabolism (yellow lines), nucleotide metabolism (red lines), carbohydrate metabolism (purple lines) and lipid metabolism (green lines) were highlighted.

(b) Distinguished serum metabolites of NKTCL, PTCL and DLBCL, comparing with healthy volunteer, were categorized into 4 subtypes according to their relevance to amino acid, nucleotide, carbohydrate, or lipid metabolism.

(c) KEGG metabolic pathway enrichment by ConsensusPathDB using distinguished serum metabolites of NKTCL, comparing with healthy volunteer.

(d) Standard amino acids significantly altered in NKTCL, comparing with healthy volunteer.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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