FIGURE

Fig. 7

ID

ZDB-FIG-220829-236

Publication

Rea et al., 2022 - Gut-derived metabolites influence neurodevelopmental gene expression and Wnt signaling events in a germ-free zebrafish model

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Fig. 7

Metabolites affect Wnt signaling. A Enriched pathway analysis of the downregulated genes in the GF group via KEGG profile. B Heatmap of 75 Wnt/β-catenin signaling genes identified by the Wnt signaling community. Box in red shows genes that are affected in our dataset. Asterisks identify two genes that were validated by RT-qPCR (C, sp5 and D, ctnnb2; one-way ANOVA of all 3 group standard weighted mean analysis, 3 independent samples, 2 degrees of freedom, total p value is as stated, error bars represent SEM). E KEGG profile output of Wnt pathway and genes from complete RNA-Seq dataset. Expression levels are shown in red where the left side (CV) is arbitrarily set to 0, the middle point is GF, and the right point is ZM

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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