FIGURE

Fig. 2

ID

ZDB-FIG-220718-66

Publication

Almstedt et al., 2021 - Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

GFP-signal measurements are representative of tumor growth. (A) Segmented time series of one representative U3013MG xenograft. Numbers indicate time (in hours) and each image is classified as Valid (green number), Invalid (red number), or Dead (white number). (B) Estimates of exponential tumor growth estimated from (A). (C) and (E) Representative light-sheet and IncuCyte images of U3180MG and U3013MG tumors (green) in zebrafish at 2 and 5 dpf. (D) and (F) Correlating tumor growth measurements of rendered surface volume (n = 20/ PDC, p < .0001 paired t-test) and IncuCyte measurements (n = 144/PDC). (G) Confocal projections showing cell nuclei (DAPI, blue), EdU staining (magenta), and tumor cells (GFP, green) injected into zebrafish at 5 dpf. Arrows indicate proliferative tumor cells. (H) Quantification of the EdU and GFP-positive tumor cell ratio at 5 dpf (n = 6/PDC).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neuro Oncol.