FIGURE

Fig. 6

ID

ZDB-FIG-220705-37

Publication

Chen et al., 2022 - Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model

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Fig. 6

Apoptosis-associated proteins and DNA fragmentation in CRMM1 cells treated with [2](PF₆)₂. (a) Western blot showing native PARP, cleaved PARP, pro-caspase-3, cleaved caspase-3 and β-actin as loading control in CRMM1 cells treated with [2](PF₆)₂ at EC_50,light (4 μM) for 24 h, irradiated or not with green light (520 nm, 15 min, 21 mW cm⁻², 19 J cm⁻²), and further incubated for 48 h in the dark. (b) DNA fragmentation in CRMM1 cells treated with [2](PF₆)₂ at EC_50,light (4 μM) for 24 h, irradiated or not with green light (520 nm, 15 min, 21 mW cm⁻², 19 J cm⁻²), and incubated in the dark for 4 h or 24 h after light irradiation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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