FIGURE
Fig. 8
- ID
- ZDB-FIG-220621-8
- Publication
- Yu et al., 2022 - A non-polar fraction of Saponaria officinalis L. acted as a TLR4/MD2 complex antagonist and inhibited TLR4/MyD88 signaling in vitro and in vivo
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Fig. 8
fr.1 and saponarin inhibited LPS microinjection-induced abnormality and mortality in zebrafish larvae. (A) Heartbeat rate of zebrafish larvae after LPS injection (0.5 mg/ml) with fr.1 (0–100 μg/ml) treatment. (B) Classification of phenotypes of zebrafish after LPS injection with fr.1. (C) Critical abnormalities morphologically observed under microscopy after LPS injection in fr.1. (D) Heartbeat rate of zebrafish larvae after LPS injection (0.5 mg/ml) with saponarin (0–100 μg/ml) treatment. (E) Classification of phenotypes of zebrafish after LPS injection with saponarin. (F) Critical abnormalities morphologically observed under microscopy after LPS injection in saponarin. ###p < .001 versus negative control larvae, and ***p < .001 versus LPS treated larvae. (n = 20 in each group).
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Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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