FIGURE

Figure 4

ID

ZDB-FIG-211129-68

Publication

Su et al., 2021 - Xylose-configured cyclophellitols as selective inhibitors for glucocerebrosidase

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Figure 4

(A) ABP labeling of β‐d‐glucosidases. A lysate of HEK293T cells expressing human GBA, GBA2 and GBA3 was incubated with indicated ABPs (6, 9 or 10) for 30 min at pH 6.0. Fluorescently labeled proteins were visualized after SDS‐PAGE. (B) Labeling with ABP 6 of wild type or mutant GBA2 (E527G nucleophile mutation and D667G acid/base mutation) expressed in HEK293T cells.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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