FIGURE

Fig. 3

ID

ZDB-FIG-210518-81

Publication

Sheets et al., 2021 - How Zebrafish Can Drive the Future of Genetic-based Hearing and Balance Research

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Fig. 3

GFP-based forward genetic screen reveals mutants with swollen afferent terminals. (a–b) The Tg(neurod1:EGFP)^nl1 transgenic line can be used to visualize the afferent terminals beneath hair cells in the lateral line (a–b, green), while the vital dye FM 4-64 can be used to visualize lateral line hair cells (a, b, magenta). Actr10^nl15 mutants were isolated in a forward genetic screen using Tg(neurod1:EGFP)^nl1 to identify mutants with swollen lateral line afferent terminals (b) (Drerup et al. 2017). Hair cells in these mutant do not label with FM 4-64. Arrowheads indicate swellings in b. Images were taken at 5 dpf at × 63 magnification. Scale bar in b = 5 µm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Assoc. Res. Otolaryngol.