FIGURE

Fig. 6

ID

ZDB-FIG-200311-7

Publication

Farkas et al., 2019 - Discovering the chloride pathway in the CFTR channel

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Fig. 6

Coupling helix 4 dynamics is strongly coupled to the bottleneck region. Optimal and suboptimal paths in the network of amino acids (spheres), connected by edges (lines) corresponding to correlation in motions, were determined. Number of suboptimal paths between coupling helix 4 (CH4, L1065) and R334 (a) is significantly higher than paths from any other coupling helix, such as from coupling helix 2 (CH2, V272) to R334 (b). Red: optimal paths; blue: suboptimal paths; orange: source residue; yellow: sink residue

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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