FIGURE

Fig. 2

ID

ZDB-FIG-191230-1506

Publication

Schenk et al., 2019 - Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model

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Fig. 2

Cellular expression of HPS proteins was analyzed by immunohistochemistry in human kidney sections. (A) Localization of HPS 1 expression in glomeruli was present at a medium level, while high expression of HPS1 was prevalent in tubuli (https://www.proteinatlas.org/ENSG00000107521-HPS1/tissue/kidney). Expression of HPS3 in glomeruli was high, while a dominant expression in tubuli was detected (https://www.proteinatlas.org/ENSG00000163755-HPS3/tissue/kidney). HPS4 showed only minor expression in glomeruli, however, strong expression in tubuli was present (https://www.proteinatlas.org/ENSG00000100099-HPS4/tissue/kidney). No data on HPS5 protein expression can be accessed through Protein Atlas (https://www.proteinatlas.org/ENSG00000110756-HPS5/tissue/kidney). All described data were obtained using Protein Atlas Version 18. (B) Data on presence of HPS protein subtypes in human kidney sections. Data on HPS expression pattern is pooled from three kidney sections each. Furthermore, the number of patients included, the mean age, sex ratio and the renal RNA expression are stated.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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