FIGURE

Fig. 9

ID

ZDB-FIG-190826-26

Publication

Zhang et al., 2019 - Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish

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Fig. 9

Butyrate further supported the differentiated state of microbiotas associated with LGG EPS or BL23 EPS. Adult zebrafish (1-month-old) were fed with the control diet, HF diet, or HF diet supplemented with 1.0% BL23 EPS or 1.0% LGG EPS for 4 weeks. Intestinal acetate levels (a), propionate levels (b), isobutyrate levels (c), butyrate levels (d) in zebrafish fed different diets which was performed with gas chromatography-mass spectrometry (n = 3). e The O₂ concentration in the intestinal mucosa layer of zebrafish fed with different diets for 4 weeks (n = 3). fRepresentative images of hypoxyprobe immunostaining in the intestine of zebrafish fed with different diets for 4 weeks. The scale bar is 50 μm. Data are expressed as the mean ± SEM. Graph bars labelled with different letters on top represent statistically significant results (P < 0.05), whereas bars with the same letter corresponds to results that show no statistically significant differences

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	high fat chemical treatment by diet: exopolysaccharide, high fat
Observed In:	intestine acetate intestine butyrate intestine dioxygen intestine isobutyrate intestine propionate
Stage:	Days 30-44

Phenotype Detail

Acknowledgments

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