FIGURE

Fig. 8

ID

ZDB-FIG-190723-666

Publication

Nittoli et al., 2019 - Characterization of paralogous uncx transcription factor encoding genes in zebrafish

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Fig. 8

Regulation of uncx gene expression in relation to Fgf, Nodal and Notch/Delta signaling pathways. Whole-mount in situ hybridization of (A, E, H, I) uncx4.1 and (B–D, E, G, J) uncx at (A) 34 hpf, (B–D) 19 h post fertilization (hpf), (E, F, H) 24 hpf, (G) 18 hpf, and (J) 19 hpf. Lateral view, anterior to left. Expression of (A) uncx4.1 and (B) uncx in acerebellar (ace) mutant embryo at (A) 34 hpf and (B) 19 hpf. (C, D) Expression of uncx in embryos treated with (C) DMSO and (D) SU5402 at 19 hpf. (E, F) Expression of (E) uncx4.1 and (F) uncx in cyclops (cyc) mutant embryo at 24 hpf (controls in Fig. 3F and 5H, respectively). (G) Expression of uncx in embryo treated with SB431542 at 18 hpf (control in Fig. 5B). (H–J) Expression of (H, I) uncx4.1 and (J) uncx in embryos treated with (H) DMSO and (I, J) DAPT at (H, I) 24 hpf and (J) 19 hpf. (J) Control in (C).

Expression Data

Genes:	uncx uncx4.1
Fish:	AB fgf8a^{ti282a/ti282a} Df(Chr12:hhex,ndr2)b16/b16
Condition:	chemical treatment: DAPT
Anatomical Terms:	somite somite ventral side somite ventro-lateral margin
Stage Range:	20-25 somites to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fgf8a^{ti282a/ti282a}
Observed In:	somite
Stage Range:	20-25 somites to Prim-15

Phenotype Detail

Acknowledgments

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