ZFIN ID: ZDB-FIG-190618-6
Young et al., 2019 - Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. eLIFE   8 Full text @ Elife
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Prim-25
PHENOTYPE:
Fish:
Observed In:
Stage: Prim-25

Fig. 6

Ztcf7l1a mutants show more retinal progenitor cells undergoing proliferation.

(A–B) Immunostaining detecting phosphohistone3 (PH3, green) and RFP (Tg(atoh7:GAP-RFP)cu2Tg-, red) in wildtype (A) and Ztcf7l1a-/- (B) eyes at 36hpf . Arrows indicate selected double PH3/RFP positive cells. n, nasal; t, temporal. Scale bar = 100 µm. (C–D) Plot showing the percentage of PH3-positive cells (C) data in Supplementary file 1L) and double PH3/RFP-positive cells (D), data in Supplementary file 1L). Single experiment, wildtype n = 7, Ztcf7l1a-/-n = 8, figures over the bars show p-values from unpaired t-tests.

 

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
RFP cu2Tg standard conditions Prim-25 retina neuron IHC
cu2Tg ; tcf7l1am881/m881 standard conditions Prim-25 retina neuron IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
cu2Tg ; tcf7l1am881/m881 standard conditions Prim-25 retina neuron RFP expression decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal eLIFE for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Elife