FIGURE

Fig. 3

ID
ZDB-FIG-190530-37
Publication
Wong et al., 2018 - ERK Activity Dynamics during Zebrafish Embryonic Development
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Fig. 3

Spatial and temporal map of ERK activity during the gastrula stage. (a) Lateral view, anterior to the top. (b) Dorsal view, anterior to the top. A blue bracket indicates the embryonic margin. White arrowheads mark the future hindbrain. (c) Changes of ERK activity in gastrula stage Teen embryos treated with the MEK inhibitor (3 M PD184352, n = 8). Before, 0 min; after, 60 min. (d) no tail expression in 3SS embryos treated with DMSO (n = 21) or PD184352 (n = 24) for 2 h (from shield to 75-epiboly stages). Inhibition of ERK during the gastrula stages leads to failures of mesodermal cell patterning in notochord and tail bud. Scale bar, 100 m.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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