ZFIN ID: ZDB-FIG-190102-5
Liu et al., 2017 - Inhibition of Cdk5 Promotes β-cell Differentiation from Ductal Progenitors. Diabetes   67(1):58-70 Full text @ Diabetes
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Condition:
Anatomical Terms:
Stage: Day 6
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage: Day 6

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP um14Tg chemical treatment by environment: LY-411575 Day 6 pancreas IHC
um14Tg ; cdk5ki110/ki110 chemical treatment by environment: LY-411575 Day 6 pancreas IHC
GFP cdk5ki110/ki110 ; zf5Tg chemical treatment by environment: LY-411575 Day 6 endocrine pancreas pancreatic B cell IHC
Day 6 exocrine pancreas pancreatic B cell IHC
s960Tg control Day 6 exocrine pancreas pancreatic B cell IHC
s960Tg ; cdk5ki110/ki110 control Day 6 exocrine pancreas pancreatic B cell IHC
zf5Tg chemical treatment by environment: LY-411575 Day 6 endocrine pancreas pancreatic B cell IHC
Day 6 exocrine pancreas pancreatic B cell IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-gcg IHC WT control Day 6 exocrine pancreas pancreatic A cell
IHC cdk5ki110/ki110 control Day 6 exocrine pancreas pancreatic A cell
Ab3-sst IHC WT control Day 6 exocrine pancreas pancreatic D cell
IHC cdk5ki110/ki110 control Day 6 exocrine pancreas pancreatic D cell
Phenotype Details
Fish Conditions Stage Phenotype
cdk5ki110/ki110 ; zf5Tg chemical treatment by environment: LY-411575 Day 6 endocrine pancreas pancreatic B cell increased amount, exacerbated
cdk5ki110/ki110 ; zf5Tg chemical treatment by environment: LY-411575, chemical treatment by environment: (R)-DRF053 hydrochloride hydrate Day 6 endocrine pancreas pancreatic B cell increased amount, exacerbated
s960Tg ; cdk5ki110/ki110 control Day 6 exocrine pancreas pancreatic B cell increased amount, abnormal
zf5Tg chemical treatment by environment: LY-411575 Day 6 endocrine pancreas pancreatic B cell increased amount, abnormal
zf5Tg chemical treatment by environment: LY-411575, chemical treatment by environment: (R)-DRF053 hydrochloride hydrate Day 6 endocrine pancreas pancreatic B cell increased amount, exacerbated
Full text @ Diabetes