FIGURE

Fig. 5

ID

ZDB-FIG-180829-14

Publication

Liu et al., 2018 - CRMP2 and CRMP4 Are Differentially Required for Axon Guidance and Growth in Zebrafish Retinal Neurons

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Fig. 5

CRMP2 synergized with CRMP4 in axon growth but not axon guidance. A half dose of either CRMP2 or CRMP4 MOs was injected singly or in combination. (a, b) Representative examples of knocking down effects of CRMP2 and CRMP4 MOs in combination. (c) The combination of the two MOs causes a significantly higher percentage of axon growth defects than the sum of the defects caused by adding up the single half doses (Fisher’s exact test, ). (d) No obvious synergy between the two CRMPs in retinal axon guidance. The doses of MOs are labeled under each column. The numbers in parentheses above each column indicate the amount of eyes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-dpysl3 + MO3-dpysl2b
Knockdown Reagents:	MO1-dpysl3 MO3-dpysl2b
Observed In:	retinal neural layer axon
Stage:	Day 4

Phenotype Detail

Acknowledgments

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