FIGURE

Fig. 3

ID

ZDB-FIG-180622-55

Publication

Gestri et al., 2018 - Cell Behaviors during Closure of the Choroid Fissure in the Developing Eye

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Fig. 3

Failure of choroid fissure fusion in eyes derived from optic vesicles with reduced POM. (A–C) Brightfield images of two host embryos at different stages after optic vesicle transplantation (at 12 ss, about 14 h pf), showing location of the ectopic eye on the yolk. Arrowheads indicate the open choroid fissure in the ectopic eyes. (D,E) Methylene blue stained sagittal sections at low (D) and high (E) resolution through an ectopic eye at 5 dpf. (F–O) Images of control (F–J) and ectopic (K–O) eyes imaged either in brightfield (F,K,I,N) or by confocal microscopy (G,H,L,M,J,O) showing cell membranes (mRFP, gray) and sox10:GFP labeled POM (green) at ages shown on the panels. Arrowheads indicate the choroid fissure. Asterisk in O' indicates retinal ganglion cell axons. The position of the lens is indicated with a white circle in (H) and (M). ee, ectopic eye; i, intestine; sc, spinal cord; y, yolk. Scale bars 50 μM.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.