FIGURE

Fig. 4

ID
ZDB-FIG-180321-5
Publication
Hozumi et al., 2017 - Nuclear movement regulated by non-Smad Nodal signaling via JNK is associated with Smad signaling during zebrafish endoderm specification
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Fig. 4

MTOC reorientation in LMCs is regulated by Nodal/JNK signaling. (A) Illustration of MTOC positioning (black dots) in LMCs. a, the minimum distance between the most vegetal position of MTOCs and the blastoderm/YSL boundary; b, length of the LMC. (B-G) Transverse sections of WT and of embryos treated with SB505124, SB431542, SP600125 or EMD 420123. MTOCs, cell membrane and nuclei are visualized by γ-tub, β-cat and DAPI staining, respectively at 4.0 and/or 4.7 hpf. Scale bars: 10 µm. (H) a/b ratio in WT and inhibitor-treated embryos at 4.0 or 4.7 hpf. n, number of nuclei examined. ***P<0.001.

Expression Data

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Antibody Labeling
Phenotype Data

Phenotype Detail
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