FIGURE

Fig. 2

ID

ZDB-FIG-170117-16

Publication

Sidhaye et al., 2016 - The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease

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Fig. 2

The zebrafish gsp/myoVb mutant exhibits a smooth intestine phenotype during 4 to 6 days post-fertilisation.

The bright field images of developing zebrafish wild type larvae (A, E, I) and their intestines (C, G, K) exhibit rough intestinal walls indicating the presence of tissue folds. The gsp/myoVb mutant larvae (B, F, J) and their intestines (D, H, L) show smooth intestinal walls suggesting absence of intestinal folds. Arrows point to the intestine in all images. Histological sections (M) of different parts of the gut of wild type sibling and gsp/myoVb mutant. In total 4 wild type siblings and 4 mutants were analysed by histology. Abbreviation: sib = sibling.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	myo5b^{t30834/t30834}
Observed In:	digestive tract morphogenesis intestinal epithelial cell differentiation intestine
Stage Range:	Day 4 to Day 6

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 142, Sidhaye, J., Pinto, C.S., Dharap, S., Jacob, T., Bhargava, S., Sonawane, M., The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease, 62-74, Copyright (2016) with permission from Elsevier. Full text @ Mech. Dev.