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General Information
ZIRC
ZFIN ID: ZDB-FIG-161027-29
Cox et al., 2016 - Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature cell biology   18(8):886-96 Full text @ Nat. Cell Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Antibody:
Fish:
Condition:
Anatomical Term:
Stage: Adult
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Adult

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression DetailsNo data available
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab6-pcna IHC AB control Adult liver
IHC AB chemical treatment: methionine sulfoximine Adult liver
IHC s705Tg control Adult liver
IHC s705Tg chemical treatment: methionine sulfoximine Adult liver
Phenotype Details
Fish Conditions Stage Phenotype
s705Tg control Adult liver increased mass, abnormal
Adult liver cell population proliferation increased occurrence, abnormal
Adult liver glutamate-ammonia ligase activity increased occurrence, abnormal
Adult liver nucleotide biosynthetic process increased occurrence, abnormal
s705Tg chemical treatment: methionine sulfoximine Adult liver size, ameliorated
Adult liver cell population proliferation occurrence, ameliorated
Adult liver glutamate-ammonia ligase activity occurrence, ameliorated
Adult liver nucleotide biosynthetic process occurrence, ameliorated
Full text @ Nat. Cell Biol.