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General Information
ZIRC
ZFIN ID: ZDB-FIG-161027-24
Cox et al., 2016 - Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature cell biology   18(8):886-96 Full text @ Nat. Cell Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Antibodies:
Fish:
Conditions:
Anatomical Term:
Stage: Adult
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Day 5 to Adult

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression DetailsNo data available
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab5-akt WB AB control Adult liver
WB AB chemical treatment: methionine sulfoximine Adult liver
WB AB chemical treatment: sirolimus Adult liver
WB s705Tg control Adult liver
WB s705Tg chemical treatment: methionine sulfoximine Adult liver
WB s705Tg chemical treatment: sirolimus Adult liver
Ab5-rps6 WB AB control Adult liver
WB AB chemical treatment: methionine sulfoximine Adult liver
WB AB chemical treatment: sirolimus Adult liver
WB s705Tg control Adult liver
WB s705Tg chemical treatment: methionine sulfoximine Adult liver
WB s705Tg chemical treatment: sirolimus Adult liver
Ab9-rps6 WB AB control Adult liver
WB AB chemical treatment: methionine sulfoximine Adult liver
WB AB chemical treatment: sirolimus Adult liver
WB s705Tg control Adult liver
WB s705Tg chemical treatment: methionine sulfoximine Adult liver
WB s705Tg chemical treatment: sirolimus Adult liver
Ab11-akt WB AB control Adult liver
WB AB chemical treatment: methionine sulfoximine Adult liver
WB AB chemical treatment: sirolimus Adult liver
WB s705Tg control Adult liver
WB s705Tg chemical treatment: methionine sulfoximine Adult liver
WB s705Tg chemical treatment: sirolimus Adult liver
Phenotype Details
Fish Conditions Stage Phenotype
AB chemical treatment: methionine sulfoximine Adult liver ab5-akt labeling increased amount, abnormal
Adult liver ab9-rps6 labeling increased amount, abnormal
AB chemical treatment: sirolimus Adult liver ab5-akt labeling decreased amount, abnormal
AB chemical treatment: sirolimus Adult liver ab9-rps6 labeling decreased amount, abnormal
s705Tg chemical treatment: methionine sulfoximine Adult liver ab9-rps6 labeling increased amount, abnormal
Adult liver ab5-akt labeling increased amount, abnormal
s705Tg chemical treatment: sirolimus Adult liver ab5-akt labeling decreased amount, abnormal
Adult liver ab9-rps6 labeling decreased amount, abnormal
s705Tg ; as3Tg control Day 5 liver increased size, abnormal
s705Tg ; as3Tg chemical treatment: methionine sulfoximine Day 5 liver size, ameliorated
s705Tg ; as3Tg chemical treatment: methionine sulfoximine, chemical treatment: sirolimus Day 5 liver size, ameliorated
s705Tg ; as3Tg chemical treatment: sirolimus Day 5 liver size, ameliorated
Full text @ Nat. Cell Biol.