FIGURE

Fig. S4

ID

ZDB-FIG-151110-23

Publication

D'Aniello et al., 2015 - Rdh10a Provides a Conserved Critical Step in the Synthesis of Retinoic Acid during Zebrafish Embryogenesis

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Fig. S4

Functional interaction between Rdh10a depletion and Aldh1a2 inhibition in the hindbrain.

(A-D) ISH for eng2a (blue), which marks the midbrain-hindbrain boundary, and egr2b (red), which marks rhombomeres (r) 3 and 5. Control DMSO treated (n = 13), Rdh10a deficient embryos (n = 13), 0.05 µM DEAB treated (n = 12), and Rdh10a deficient + 0.05 µM DEAB embryos (n = 14). (E) Schematic and measurements of r5 length in arbitrary units (AU). Asterisks indicate a statistical significant difference between embryos treated with the DMSO versus all the other conditions. Hashtag indicates a statistically significant difference between embryos injected with rdh10a MOs or treated with DEAB versus the embryos treated with DEAB and injected with rdh10a MOs.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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