ZFIN ID: ZDB-FIG-150922-5
Li et al., 2015 - Integrative Analysis of Circadian Transcriptome and Metabolic Network Reveals the Role of De Novo Purine Synthesis in Circadian Control of Cell Cycle. PLoS Computational Biology   11:e1004086 Full text @ PLoS Comput. Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-15 to Day 5

Fig. S4

The phenotypes of WT, control morphant, and three impdh morphants at early stages of development.

(A) impdh1b morphant development was faster than WT or control larvae while the impdh2 morphant grew slower at 32 hpf and 52 hpf. (B) The body lengths were calculated in 5 dpf larvae. impdh1b knock-down promotes larval zebrafish development significantly. Error bars represent the standard error of mean (SEM) among independent replicates. * p<0.05; ***P<0.001, unpaired two-tailed Student’s t-test, scale bars, 500μm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-impdh1a standard conditions Day 5 whole organism decreased length, abnormal
AB + MO1-impdh1b standard conditions Prim-15 - Long-pec developmental growth increased rate, abnormal
Day 5 whole organism increased length, abnormal
AB + MO1-impdh2 standard conditions Prim-15 - Long-pec developmental growth decreased rate, abnormal
Day 5 whole organism decreased length, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS Computational Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS Comput. Biol.