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ZIRC
ZFIN ID: ZDB-FIG-150820-45
Dooley et al., 2013 - Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease. Pigment cell & melanoma research   26(2):205-217 Full text @ Pigment Cell Melanoma Res.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Knockdown Reagent:
Observed In:
Stage Range: Prim-25 to Day 4

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TU + MO1-atp6v1h standard conditions Long-pec melanocyte melanosome circular, abnormal
Long-pec melanocyte melanosome decreased pigmentation, abnormal
Long-pec melanocyte melanosome decreased size, abnormal
Long-pec pigmentation disrupted, abnormal
Day 4 melanocyte melanosome circular, abnormal
Day 4 melanocyte melanosome decreased pigmentation, abnormal
Day 4 melanocyte melanosome decreased size, abnormal
Day 4 pigmentation disrupted, abnormal
slc45a2b4/b4 control Day 4 melanocyte melanosome unpigmented, abnormal
Day 4 pigmentation disrupted, abnormal
slc45a2b4/b4 chemical treatment: bafilomycin A1 Prim-25 melanocyte melanosome decreased pigmentation, abnormal
Prim-25 pigmentation disrupted, abnormal
slc45a2b4/b4 + MO1-atp6v1h standard conditions Day 4 melanocyte melanosome decreased pigmentation, abnormal
Day 4 pigmentation disrupted, abnormal
slc45a2tnr39/tnr39 control Long-pec melanocyte melanosome circular, abnormal
Long-pec melanocyte melanosome decreased pigmentation, abnormal
Long-pec melanocyte melanosome decreased size, abnormal
Long-pec pigmentation disrupted, abnormal
slc45a2tnr39/tnr39 + MO1-atp6v1h standard conditions Long-pec melanocyte melanosome decreased pigmentation, abnormal
Long-pec pigmentation disrupted, abnormal
Full text @ Pigment Cell Melanoma Res.