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General Information
ZIRC
ZFIN ID: ZDB-FIG-150820-44
Dooley et al., 2013 - Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease. Pigment cell & melanoma research   26(2):205-217 Full text @ Pigment Cell Melanoma Res.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Protruding-mouth

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment: N-phenylthiourea Protruding-mouth eye photoreceptor cell membrane immature, abnormal
Protruding-mouth retinal pigmented epithelium melanosome decreased amount, abnormal
Protruding-mouth retinal pigmented epithelium melanosome degenerate, abnormal
Protruding-mouth retinal pigmented epithelium melanosome irregularly shaped, abnormal
slc24a5b1/b1 standard conditions Protruding-mouth retinal pigmented epithelium melanosome decreased pigmentation, abnormal
slc45a2b4/+; slc45a2tm83a/+ standard conditions Protruding-mouth retinal pigmented epithelium melanosome decreased pigmentation, abnormal
slc45a2b4/b4 standard conditions Protruding-mouth retinal pigmented epithelium melanosome amount, normal
Protruding-mouth retinal pigmented epithelium melanosome decreased pigmentation, abnormal
slc45a2ti225/ti225 standard conditions Protruding-mouth retinal pigmented epithelium melanosome decreased pigmentation, abnormal
slc45a2tj20e/tj20e standard conditions Protruding-mouth retinal pigmented epithelium melanosome decreased pigmentation, abnormal
slc45a2tnr39/+; slc45a2b4/+ standard conditions Protruding-mouth retinal pigmented epithelium melanosome decreased pigmentation, abnormal
tyrtk20/tk20 standard conditions Protruding-mouth eye photoreceptor cell membrane immature, abnormal
Protruding-mouth retinal pigmented epithelium melanosome absent, abnormal
Full text @ Pigment Cell Melanoma Res.