ZFIN ID: ZDB-FIG-150423-50
Zancan et al., 2015 - Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling. Human molecular genetics   24(5):1280-94 Full text @ Hum. Mol. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Prim-15 to Days 30-44
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-15 to Days 30-44

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
DsRed gbasa1621/sa1621; gz15Tg standard conditions Days 30-44 liver IFL
gz15Tg control Days 7-13 liver IFL
gz15Tg standard conditions Days 30-44 liver IFL
gz15Tg + MO2-gba standard conditions Days 7-13 liver IFL
sd2Tg control Protruding-mouth nucleate erythrocyte IFL
sd2Tg + MO2-gba standard conditions Protruding-mouth nucleate erythrocyte IFL
EGFP la2Tg control Day 5 thromboblast ISH
Day 5 thrombocyte ISH
la2Tg + MO2-gba standard conditions Day 5 thromboblast ISH
Day 5 thrombocyte ISH
myb WT control Prim-15 intermediate cell mass of mesoderm hematopoietic stem cell ISH
WT + MO2-gba standard conditions Prim-15 intermediate cell mass of mesoderm hematopoietic stem cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO2-gba standard conditions Prim-15 definitive hemopoiesis occurrence, abnormal
Prim-15 hematopoietic stem cell mislocalised, abnormal
gbasa1621/sa1621; gz15Tg standard conditions Days 30-44 liver increased size, abnormal
Days 30-44 spleen increased size, abnormal
gz15Tg + MO2-gba standard conditions Days 7-13 liver increased size, abnormal
la2Tg + MO2-gba standard conditions Day 5 hematopoietic system has fewer parts of type thrombocyte, abnormal
Day 5 thrombocyte differentiation decreased occurrence, abnormal
sd2Tg + MO2-gba standard conditions Protruding-mouth hematopoietic system has fewer parts of type nucleate erythrocyte, abnormal
Full text @ Hum. Mol. Genet.