FIGURE

Fig. 5

ID

ZDB-FIG-150330-23

Publication

Miller et al., 2015 - Neurobeachin Is Required Postsynaptically for Electrical and Chemical Synapse Formation

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Fig. 5

nbea Mutants Have Defects in Eliciting Normal Behavior

(A–D) Individual frames from a 500 fps movie. Arrowheads point to eyes. Auditory startle stimulus was applied at time = 0 (ms = millisecond).

(A) M is responsible for a fast-escape response to threatening stimuli and initiates a turn away from stimulus that is completed in 10 ms.

(B–D) nbea mutant animals often fail to initiate turns (B) and are frequently found lying on their side (C). However, when they do respond, the behavior produced is indistinguishable from wild-type (D).

(E and F) Quantitation of escape response and balance defects in a separate wild-type line (wt), nbea mutant animals, and their wt siblings (wt sibs). Each animal was tested in three separate trials for its response to stimulus. The average number of trials with response (E) or with animals on their sides (F) was recorded. Graphs represent data as mean ± SEM from three separate trials. p < 0.05 compared to control; ns, not significant.

Associated experimental statistics are found inTable S3.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nbeaa^fh364/fh364 (AB/TU)
Observed In:	behavior response to gravity startle response
Stage:	Day 6

Phenotype Detail

Acknowledgments

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