ZFIN Figure: Yuan et al., 2014, Fig. 3

ZFIN ID: ZDB-FIG-150324-12

ZFIN ID: ZDB-FIG-150324-12

Yuan et al., 2014 - The translation initiation factor Eif3i upregulates vascular endothelial growth factor A, accelerates cell proliferation, and promotes angiogenesis in embryonic development and tumorigenesis. The Journal of biological chemistry 289(41):28310-23 Full text @ J. Biol. Chem.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	fli1 GFP
Fish:	WT eif3i^{la010697Tg/la010697Tg} la116Tg eif3i^{la010697Tg/la010697Tg}; la116Tg
Anatomical Terms:	dorsal aorta intersegmental vessel pectoral fin blood vessel vasculature
Stage:	Prim-5

PHENOTYPE:

Fish:	eif3i^{la010697Tg/la010697Tg} eif3i^{la010697Tg/la010697Tg}; la116Tg
Observed In:	intersegmental vessel sprouting angiogenesis
Stage:	Prim-5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
fli1	WT	standard conditions	Prim-5	dorsal aorta	ISH
			Prim-5	intersegmental vessel	ISH
			Prim-5	pectoral fin blood vessel	ISH
	eif3i^{la010697Tg/la010697Tg}	standard conditions	Prim-5	dorsal aorta	ISH
			Prim-5	intersegmental vessel	ISH
			Prim-5	pectoral fin blood vessel	ISH
GFP	eif3i^{la010697Tg/la010697Tg}; la116Tg	standard conditions	Prim-5	intersegmental vessel	IFL
			Prim-5	vasculature	IFL
	la116Tg	standard conditions	Prim-5	intersegmental vessel	IFL
			Prim-5	vasculature	IFL

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
eif3i^{la010697Tg/la010697Tg}	standard conditions	Prim-5	intersegmental vessel malformed, abnormal
eif3i^{la010697Tg/la010697Tg}; la116Tg	standard conditions	Prim-5	intersegmental vessel malformed, abnormal
		Prim-5	sprouting angiogenesis process quality, abnormal

Full text @ J. Biol. Chem.