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ZFIN ID: ZDB-FIG-150311-74
Terashima et al., 2014 - Odd skipped related 1 is a negative feedback regulator of Nodal-induced endoderm development. Developmental dynamics : an official publication of the American Association of Anatomists   243(12):1571-80 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Terms:
Stage: Shield
PHENOTYPE:
Fish:
Observed In:
Stage: Shield

Fig. 2 osr1 expression is disrupted in Nodal signaling mutants. A–D: Animal pole views. A′–D′: Dorsal views of the shield. At shield stage, osr1 is expressed in the shield and germ ring of the embryo (A, A′). Maternal zygotic one eyed pinhead (MZoep) mutants, which lack all Nodal signaling, show a complete loss of osr1 expression (B, B′). Mutants bonnie and clyde(bon) and schmalspur(sur), which have reduced Nodal signaling, show a reduction of osr1 expression (C, C′ and D, D′, respectively).

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
osr1 AB/TU standard conditions Shield germ ring ISH
Shield shield ISH
foxh1m768/m768 standard conditions Shield germ ring ISH
Shield shield ISH
mixl1m425/m425 standard conditions Shield germ ring ISH
Shield shield ISH
tdgf1tz257/tz257 standard conditions Shield Not Detected germ ring ISH
Shield Not Detected shield ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
foxh1m768/m768 standard conditions Shield germ ring poorly differentiated, abnormal
Shield shield poorly differentiated, abnormal
mixl1m425/m425 standard conditions Shield germ ring poorly differentiated, abnormal
Shield shield poorly differentiated, abnormal
tdgf1tz257/tz257 standard conditions Shield germ ring poorly differentiated, abnormal
Shield shield poorly differentiated, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.