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General Information
ZIRC
ZFIN ID: ZDB-FIG-141112-1
Molt et al., 2014 - Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance. Journal of Cell Science   127(Pt 16):3578-92 Full text @ J. Cell Sci.
EXPRESSION / LABELING:
Gene:
Antibodies:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: 14-19 somites to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-5 to Protruding-mouth

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
pgm5 WT standard conditions 14-19 somites somite ISH
Prim-5 gut ISH
Prim-5 head ISH
Prim-5 somite ISH
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-actn IHC WT standard conditions Prim-5 - Protruding-mouth muscle Z disc
Ab3-ttn IHC WT control Protruding-mouth muscle Z disc
IHC WT + MO1-pgm5 standard conditions Protruding-mouth muscle Z disc
Ab6-lam IHC WT standard conditions Prim-5 - Protruding-mouth myoseptum
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-pgm5 standard conditions Prim-5 musculoskeletal movement decreased process quality, abnormal
Prim-5 skeletal muscle paralysed, abnormal
Protruding-mouth skeletal muscle disorganized, abnormal
Protruding-mouth skeletal muscle morphology, abnormal
Protruding-mouth skeletal muscle cell detached from somite border, abnormal
Protruding-mouth striated muscle cell misaligned with striated muscle cell, abnormal
Protruding-mouth striated muscle cell myofibril disorganized, abnormal
Protruding-mouth striated muscle cell myofilament detached from myoseptum, abnormal
Protruding-mouth striated muscle cell myofilament disorganized, abnormal
Protruding-mouth striated muscle cell Z disc misaligned with striated muscle cell Z disc, abnormal
Full text @ J. Cell Sci.