FIGURE

Fig. 6

ID

ZDB-FIG-140709-15

Publication

Chang-Chien et al., 2014 - The connexin 30.3 of zebrafish homologue of human connexin 26 may play similar role in the inner ear

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Fig. 6

Zebrafish Cx30.3 proteins expressed in the cell membrane of hair cells of adult inner ear. Zebrafish Cx30.3 protein is expressed in the cell membrane of hair cells of the adult inner ear. Confocal images of sections from the adult inner ear that were immunostained with antibodies against zebrafish Cx30.3, acetylated tubulin (a hair cell marker) and pan-cadherin (a cell membrane marker) are displayed. The Cx30.3 protein, indicated by yellow arrows, is expressed at higher levels in supporting cells (SC) than in hair cells (HC) of maculae (A-D). In addition, the Cx30.3 protein localized to the cell membrane of hair cells (E-H). Sections from the adult inner ear were counterstained with DAPI to highlight the nuclei. Scale bars represent 10 µm. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Antibodies:	Ab1-cx30.3 Ab1-tuba Ab2-pan-cadherin
Fish:	WT
Anatomical Terms:	auditory epithelial support cell plasma membrane hair cell plasma membrane inner ear hair cell inner ear plasma membrane
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Hearing Research, 313, Chang-Chien, J., Yen, Y.C., Chien, K.H., Li, S.Y., Hsu, T.C., Yang, J.J., The connexin 30.3 of zebrafish homologue of human connexin 26 may play similar role in the inner ear, 55-66, Copyright (2014) with permission from Elsevier. Full text @ Hear. Res.