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ZFIN ID: ZDB-FIG-130318-2
Eisa-Beygi et al., 2013 - The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway. Developmental Biology   373(2):258-266 Full text @ Dev. Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: 20-25 somites to Long-pec

Fig. S2 Embryos with cerebral hemorrhage have normal vascular patterning and no regression. (A-F) Representative photomicrographs of Tg(fli1:EGFP) embryos exposed to DMSO or 0.5 mg/L ATV and imaged at 14 hpf (A, B), 26 hpf (C, D) and 48 hpf (E, F). White asterisks indicate abnormally dilated PPrA and PMBC. Anterior is to the left and dorsal to the top. Scale bars = 200 μm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
y1Tg chemical treatment: drug 20-25 somites - Long-pec branching involved in blood vessel morphogenesis process quality, normal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 373(2), Eisa-Beygi, S., Hatch, G., Noble, S., Ekker, M., and Moon, T.W., The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway, 258-266, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.