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ZIRC
ZFIN ID: ZDB-FIG-121105-6
Zhang et al., 2010 - Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers. Proceedings of the National Academy of Sciences of the United States of America   107(39):16940-16945 Full text @ Proc. Natl. Acad. Sci. USA
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Adult

Fig. 2

Array CGH analysis of copy-number changes in zebrafish MPNSTs. Heatmap showing aCGH results indicating relative chromosomal gain (red) and loss (blue) in 36 zebrafish tumor/normal sample pairs across chromosomes 1–25. Thirty-one rp tumor samples are shown on the top and five p53 tumor samples are shown on the bottom. The heatmap is colored according to the segment mean of the data as processed by a circular binary segmentation algorithm, with segment mean values between −0.01 and 0.01 displayed white, and segment mean values between 0.01 (−0.01) and 0.8 (−0.8) displayed in continuous shades of red (blue) on a quasilogarithmic scale (see color band at the bottom). Segment mean values above (below) 0.8 (−0.8) are rendered in the most saturated color value.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
rpl14hi823Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rpl35hi258Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rpl36ahi10Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rpl7hi1061Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps11hi2799Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps15ahi2649Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps18hi1026Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps29hi2903Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps3ahi1290Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps5hi1364aTg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps5hi577bTg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps7hi1034bTg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
rps8ahi1974Tg/+ standard conditions Adult peripheral nervous system chromosome amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Proceedings of the National Academy of Sciences of the United States of America for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Proc. Natl. Acad. Sci. USA