FIGURE

Fig. 2

ID

ZDB-FIG-120316-90

Publication

Trofka et al., 2012 - The Her7 node modulates the network topology of the zebrafish segmentation clock via sequestration of the Hes6 hub

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Fig. 2

Her proteins form DNA-binding and non-DNA-binding dimers in vivo. (A-F) Representative images of Her1 (A), Her7 (B), Hes6 (C), Her1+Her7 (D), Her1+Hes6 (E) and Her7+Hes6 (F) proteins. (G) A chart summarizing the dimers that bind DNA in vitro (denoted by a +) and the dimers that form in vivo (denoted by a green box). All the dimers observed in vitro, except Her12/Her12, were observed in vivo in addition to the presence of four novel dimers. (+/–) Her11 weakly binds DNA, and although we have observed binding in multiple independent experiments, we frequently did not detect the faint gel shift.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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