FIGURE

Fig. 4

ID
ZDB-FIG-101119-17
Publication
Dahl Ejby Jensen et al., 2009 - Nitric oxide permits hypoxia-induced lymphatic perfusion by controlling arterial-lymphatic conduits in zebrafish and glass catfish
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Fig. 4

Hypoxia-induced lymphatic perfusion is dependent on NO. (A) Tailfin lymphatic perfusion under normoxia. (Scale bar, 50 μm.) (B) Tailfin lymphatic perfusion under normoxia in zebrafish treated with 100 μM sodium nitroprusside (SNP). Under hypoxic conditions, tailfin lymphatic perfusion of (C) control zebrafish (vehicle), and zebrafish treated with (D) 1 μM l-NMMA, (E) 1 μM ODQ, (F) 10 μM c-PTIO, (G) 1 μM l-NMMA + 100 μM SNP, and (H) 1 μM ODQ + 100 μM SNP. Dashed blue lines mark the border of the lymphatics, and red dots indicate blood cells. (I) Quantification of blood cells in tailfin lymphatics under different conditions. ***, P < 0.001; NS, not significant.

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA